What's new in GLP-1?

In this CME, Janet Leung, MD discuss how to compare currently FDA approved GLP1a (and GIP/GLPa), relative efficacy to each other, and expanded indications, discuss upcoming twin and tricretins therapies that have already made the news, explain the mechanisms of action and how that explains side-effect profiles, and strategies to mitigate, focusing on GI side effects, identify concerns for muscle loss, strategies to mitigate, and upcoming pharmaceuticals under development, and describe landscape of coverage (including direct pay).

Educational Objectives 

Upon completion of this activity, participants should be able to:

• Compare currently FDA approved GLP1a (and GIP/GLPa), relative efficacy to each other, and expanded indications
• Discuss upcoming twin and tricretins therapies that have already made the news
• Explain the mechanisms of action and how that explains side-effect profiles, and strategies to mitigate, focusing on GI side effects
• Identify concerns for muscle loss, strategies to mitigate, and upcoming pharmaceuticals under development
• Describe landscape of coverage (including direct pay)

Disclosures:

All individuals in a position to control the content of this education activity have disclosed all financial relationships with any companies whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All of the relevant financial relationships for the individuals listed below have been mitigated. 

Dr. Janet Leung receives; 

• Stock: Doximity and Quest

Accreditation Statement

In support of improving patient care, the University of Pittsburgh is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

The University of Pittsburgh designates enduring material activity for a maximum of 0.75 AMA PRA Category 1 Credit[s]™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Other health care professionals will receive a certificate of attendance confirming the number of contact hours commensurate with the extent of participation in this activity.

For your credit transcript, please access our website 4 weeks post-completion at http://ccehs.upmc.com and follow the link to the Credit Transcript page.

Release Date: 11/16/2026 | Last Modified On: 11/16/2026 | Expires: 11/16/2027